Press Room

Event

AAPS 2024 PharmSci 360

Start

Sunday, October 20, 2024

End

Wednesday, October 23, 2024

Location: Salt Lake City, United States

Booth Number: 1939

Hovione is present at AAPS in October 2024, know more about the event and contact us to schedule a meeting

Visit Hovione’s booth at AAPS PharmSci 360 next October 20-23 in Salt Lake City and meet our team of experts.

The AAPS PharmSci 360 Annual Meeting is organized by the American Association of Pharmaceutical Scientists (AAPS). The event provides a platform for pharmaceutical scientists from academia, industry, government, and other institutions worldwide to exchange knowledge and discuss the latest advancements in the field.

Don't miss our experts' presentations in Salt Lake City

Oral Presentation, 155 F

Development of Spray Drying Processes Grounded on Innovative Approaches
Monday, October 21 | 10:30 AM – 11:00 AM
Presenting Author: Clara Sa Couto, Ph.D.

Short description: New BCS Class 2 drugs represent up to 70% of the pharmaceutical pipeline. Limited aqueous solubility has been one of the major hurdles in the development of oral-dosage forms, as poor solubility hinders oral bioavailability. Different formulation strategies and enabling technologies have been used to overcome low aqueous solubility, including complexation with other compounds, nano-milling and amorphous solid dispersions (ASD).
ASDs have emerged has one of the preferred methods to improve solubility, with industrially demonstrated processes and multiple approved treatments. Generally, the ASDs manufacturing methods are classified into solvent-based – spray drying (SD), electrospraying, rotary evaporation – and melting or fusion – hot-melt extrusion, KinetiSol, Three-dimensional (3D) printing.

The selection of the most suitable method depends on the nature of the API and the SD has been unanimously recognized as the leading technology due to not only the mild processing conditions but also due to scalability, commercial scale representative ASD material can be produced in laboratorial scale and kept across scales. (full description)

Key learnings:

Develop a robust process at lab scale and assure a successful scale-up
Understand how to use of mathematical models, rheological and analytical characterization, and PAT tools to improve SD process development
Understand how to use a Model Based Methodology to Establish the Design Space and a Commercial Process

Rapid Fire Presentation, 155 E

Streamlining Loss-in-Weight Feeding Process Development Using Predictive Tools
Monday, October 21 | 3:30 PM – 4:30 PM
Presenting Author: João Henriques, M.Sc.

Short description: Continuous Direct Compression (CDC) has gained increased attention due to its advantages over batch processing. In CDC, each material is individually fed into the system at a predefined rate via loss-in-weight feeders, making it essential to understand their behavior during processing. This study aimed to predict the feeding performance and ideal setup for a new material, based on material properties. This was achieved by correlating material properties and feeder setup with feeding performance. A wide range of materials, including excipients, APIs, and spray-dried excipients, were physically and rheologically characterized, and their feeding performance evaluated. Results indicate that feeding performance is predominantly influenced by variables related to density, cohesion, and flowability, which can be obtained by performing three characterization analyses. In turn, these properties determine how different setup options influence feeding behavior. This workflow allows a data-driven approach, significantly reducing the time and material spent on process development.

Key learning: In this presentation, attendees will explore the potential of using predictive strategies to develop and optimize a loss-in-weight feeding process for continuous tableting using minimum analytical and rheological characterization.

Join Hovione at our poster presentations

Dispersome® as an Advanced Platform for Oral Bioenhancement

Monday, October 21 | 12:30 PM – 1:30 PM
Authors: Ana Filipa Ferreira Ph.D., Liliana Rodrigues Ph.D., Carolina Pinheiro Ph.D., Maria Paisana Ph.D., Emmanuel Heinrich Ph.D., Ines Ramos Ph.D., Sara Pinto M.Sc.
Presenting Author: João Henriques, M.Sc.

Improving Lipid Nanoparticles Stability for mRNA Lung Delivery Through Nebulization

Tuesday, October 22 | 9:30 AM – 10:30 AM
Authors: Ricardo Miguel Velez M.Sc., Eunice Costa Ph.D., Susana Saldanha M.Sc., Rute Mota M.Sc., Luís Marques Ph.D.
Presenting Author: Eunice Costa Ph.D.

Natural-Based ASD Platforms: Enhancing Stability and Bioavailability

Tuesday, October 22 | 9:30 AM – 10:30 AM
Authors: Francisco Tavares M.Sc., Clara Sa Couto Ph.D., Joana Cotrim B.Sc., Ines Ramos Ph.D., Vanda Serra Ph.D., Maria Paisana Ph.D.
Presenting Author: Clara Sa Couto, Ph.D.

Protein Stabilization Sweet Spot: Novel Class of Sugar-Based Excipients Enabling Downstream Processing and Formulation

Tuesday, October 22 | 12:30 PM – 1:30 PM
Authors: Paulo Roque Lino, Eva C. Lourenço, Joana Diogo, Ricardo Gonçalves, Osvaldo S. Ascenso, Joana Cristóvão, Ana Filipa Ferreira, Luís Marques Ph.D.
Presenting Author: Eunice Costa Ph.D.

Let’s discuss your project together.

Find more about AAPS PharmSci 360

You might be interested in:

Drug Substance at Hovione

Your partner in custom development and manufacturing of APIs.

The Leader in Spray Drying

Know how to overcome your solubility issues with the best scale-up science.

The Future is Continuous

Meet our experts and find out if Continuous Tableting is right for your product.

Industrialization of Innovative Platforms

Learn more about our Large-scale GMP-compliant platforms that support your project from development to commercialization.

Also in the Press Room

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Why you shouldn’t neglect the importance of blending people, culture, and strategy to foster success in a business. People, customer centricity, and a clear strategy bring strong values to the forefront of every business. Fostering a workplace that inspires motivation and enhances employee satisfaction enables team members to bring their best selves to work each day, driving innovation and excellence. Earlier this year, CDMO Hovione demonstrated success by being certified as a Top Employer by the Top Employers Institute (TEI) across all four of its global manufacturing sites in Portugal, Ireland, the US, and Macau, for the third consecutive year. We spoke to board member and Senior Vice-President of Human Resources at Hovione Ilda Ventura to find out how. What specific strategies and initiatives have you implemented to maintain the company’s Top Employer status? We started the latest TEI Certification in 2023. Since then, we have been focusing on areas that can differentiate us as employers. In the US, for example, we have invested in bringing more proximity to the HR team, improving our listening strategy and the employee experience. The initiatives span from establishing better alignment between the business strategy and the people strategy, living our values and celebrating our successes. We are accelerating our global growth while strengthening our operations worldwide. It is essential for us to ensure that all our employees, regardless of their location, enjoy a consistent and unified work experience. Having all four of our sites recognized by TEI confirms that we are on the right path. What changes have been made to Hovione's recognition and rewards programs to motivate employees? By implementing a global job architecture with clear career roadmaps supported by a performance and compensation annual cycle. Everyone is eligible to merit remuneration increases and bonuses, and the corporate results are shared with everyone in a transparent way. This allows us to create a culture of recognition, where individual contributions are valued and aligned with the company's overall success. It fosters motivation and engagement, ensuring employees feel appreciated for their efforts and understand how their work directly aligns with our purpose. This culture not only enhances employee satisfaction, but strengthens our ability to attract and retain top talent. How important is it to monitor consistent employee engagement and satisfaction across global locations? Our employee engagement survey results are carefully reviewed and discussed both locally and globally, ensuring we address the unique needs of each region while driving company-wide progress. We prioritize actionable improvements that resonate with our teams, engaging cross-functional and geographically diverse groups to implement meaningful change. Across our sites, we’ve made significant investments tailored to each region while maintaining a unified approach to employee satisfaction. In the US, where employees value transparency, recognition, and growth opportunities, we’ve enhanced communication, feedback channels, and career development pathways. Similarly, in Portugal, Ireland, and Macau, we’ve introduced initiatives to promote collaboration, recognition, and personal growth, ensuring all employees experience a sense of belonging and purpose. The actions we take are closely monitored, and every improvement is shared openly across all locations, fostering a culture of trust, transparency, and celebration that connects and empowers our workforce. How are you working to attract and retain top talent in the competitive pharma industry? We continuously strive to strengthen our reputation as an employer of choice. Participating in TEI allows us to have an independent assessment of our HR efforts and initiatives, ensuring that we are continuously improving and aligning with best practices. In addition, we have robust referral programs in place, supported by the fact that over 70 percent of our employees are strong promoters of the company. This is a testament to the positive culture we’ve built, and we are focused on leveraging this strength to attract and retain top talent. In what ways does the company communicate and reinforce its core purpose and values among employees? Our motto is “In it for life” – so, for example, every year we celebrate in each site our “Victory Over Diseases” by communicating the new products that we are manufacturing, as well as the new patents and innovative ideas that contribute to fighting diseases and improving global health. Contributing to saving the lives of billions of people worldwide is a way to motivate our people to challenge themselves and push the limits of innovation. By celebrating our achievements and their impact, we inspire our teams to think creatively, embrace new challenges, and contribute to solutions that make a real difference in the world. It´s an invitation to live our purpose. Macau was the first site in the region to earn Top Employer certification last year and has renewed it this year. What unique challenges and successes have been experienced in achieving and maintaining this status in Macau? Macau is unique. It’s the only site in this industry in the territory, so we have taken advantage of that to differentiate ourselves as an employer by collaborating with universities and local authorities to offer career opportunities and benefits that are a reference in the region. What areas have you identified for continuous improvement in workplace practices and employee satisfaction in the future? We will continue to strengthen our employee value proposition by mapping the employee journey and addressing every touchpoint to enhance the overall experience. Both people and business needs are constantly changing. It requires continuous adaptation of processes to meet evolving expectations. If I had to highlight one key focus, it would be alumni engagement. The Hovione community is extensive and goes beyond our current team members. We see a clear opportunity to create an alumni program to stay connected with those who have been part of our journey. Read the full article on themedicinemaker.com

Press Clipping

The Medicine Maker, 13 February 2026

The Secret to Being a Good Employer

Feb 13, 2025

Three is the magic number for Hovione as it’s once again been certified as a top employer. For the third consecutive year, all four of its manufacturing sites - Lisbon, Cork, East Windsor in USA, and Macau - have been certified as Top Employers by the Top Employers Institute. Hovione is an international integrated pharmaceutical development and manufacturing organisation. This certification follows, Hovione said, a rigorous audit process. Jean-Luc Herbeaux, Chief Executive Officer, Hovione, explained: “This recognition reflects the exceptional dedication and collaboration of the entire Hovione team. Hovione is a development and manufacturing service company operating in one of the most demanding and regulated industries. We understand that our success is deeply rooted in our people. “Together, as One Hovione, we are committed to continuously refining our practices to foster a workplace that inspires motivation and enhances employee satisfaction, so that, every day, our team members bring their best selves to work, driving innovation and excellence at every step,” Jean-Luc added. Ilda Ventura, Senior Vice-President of Human Resources and Member of the Management Board, Hovione, said: “This distinction underscores our unwavering commitment to our people. At Hovione, we design our HR systems and processes to ensure that every team member enjoys a consistent and fulfilling experience, regardless of their role, function, or location.” Imelda Cummins, HR Director for Hovione Ireland, said: “This distinguished accreditation is a testament to our commitment to establish frameworks to attract, engage and retain top talent. We believe that our people are our greatest asset, and this recognition reflects the hard work and dedication of our entire team who strive every day to foster a culture of excellence, innovation, and collaboration. Receiving the Top Employer accreditation is motivation for us to keep pushing the boundaries of what it means to be an exceptional employer.” Hovione recently celebrated the opening of a multi-million euro expansion at its site in Ringaskiddy, which almost doubled the capacity of its spray drying facilities. Read the full article on CorkIndependent.com

Press Clipping

Cork Independent, 22 January 2025

Hovione gets top employer accolade

Jan 22, 2025

Hovione has once again solidified its position as a top employer in all four of its manufacturing sites - Lisbon (Portugal), Cork (Ireland), East Windsor (NJ, USA), and Macau. The program highlights the company’s significant advancements in several critical areas, including Purpose & Values, Diversity, Equity & Inclusion (DEI), Employer Branding, and Recognition & Rewards, driven by sustained investment in people. This certification from the Top Employers Institute follows a rigorous audit process and underscores Hovione’s consistency in investing in people and world-class workplace practices, as well as the unwavering commitment of its more than 2,300 employees to the company's core purpose and values. “This recognition reflects the exceptional dedication and collaboration of the entire Hovione team,” said Jean-Luc Herbeaux, Chief Executive Officer. “Hovione is a development and manufacturing service company operating in one of the most demanding and regulated industries. We understand that our success is deeply rooted in our people. Together, as One Hovione, we are committed to continuously refining our people practices to foster a workplace that inspires motivation and enhances employee satisfaction, so that, every day, our team members bring their best selves to work, driving innovation and excellence at every step.” Macau, which became the first company in the region to achieve Top Employer certification last year, has successfully renewed the status, solidifying Hovione’s global leadership in workplace excellence. With its consistent Top Employer recognition, Hovione demonstrates that the talent strategy is perfectly aligned with the business strategy. Watch Ilda Ventura, Senior Vice-President of Human Resources and Member of the Management Board of Hovione, video about what this certification means for Hovione. For additional information, please read the press release.

News

The certification is granted to Hovione's four manufacturing sites for the third consecutive year.