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Article / Sep 29, 2015

Hovione to expand its New Jersey facility

Manufacturing Chemist, 29 September 2015

Portuguese active pharmaceutical ingredients (APIs) and intermediates manufacturer Hovione is expanding its New Jersey facility in East Windsor, US to meet the increasing demands of its customers and to give them more options for spray drying manufacturing.

The expansion will add 30,600ft2 (2,843m2) to the 24,000ft2 (2,211m2) facility. It will include a new commercial spray dryer unit to complement the firm's existing pilot unit and this installation will be specifically designed to handle potent drug substances (APIs).

Drug substance capacity will also more than double at the site to support the needs of current and potential new customers.

Hovione said around 60 new jobs will be added to the current workforce at the plant.

 

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Integrated approach simplifies development, reduces risk, and supports scalable manufacturing. Hovione and Industrial Design Consultancy Ltd.’s (IDC) lead single-use nasal dry powder device is now available for commercial partnerships. Hovione and IDC have completed the device design and established initial device manufacturing and supply capability, enabling pharmaceutical partners to leverage existing capsule filling infrastructure. This approach simplifies development, reduces cost and risk, and helps shorten timelines to the clinic and commercialization. “This milestone marks an important step in the evolution of our collaboration with IDC — from device innovation to a fully integrated intranasal drug delivery platform,” said Márcio Temtem, Ph.D., Vice President, Strategic Business Management, Hovione. “As the industry looks for faster, more reliable ways to bring complex therapies to patients, integration becomes critical. By bringing together nasal particle engineering science, formulation manufacturing and filling, and device technologies into a single offering, we enable a more seamless and predictable development journey, accelerating the path to market for intranasal therapies.” The nasal delivery device enables broad and targeted nasal deposition flexibility while delivering maximum usability and reliability. With a patented design and manufacturing process established, the platform is available for partnering with pharmaceutical companies on an exclusive basis as part of Hovione’s integrated offering for inhalation and nasal drug development and manufacturing. Additionally, IDC’s Managing Director, Stephen Knowles Ph.D., said the companies are now “well-advanced” with the development of a multi-use device to support an even wider range of therapies and patient needs. Read the full article at ContractPharma.com    

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