Knowledge Center

Poster / Oct 18, 2021

Spray-Dried Composite Formulation Containing DSPC for Lung Sustained Release

  • Beatriz Noriega Fernandes
AAPS 2021

Track: Formulation and Delivery – Chemical
Monday, October 18, 2021 | 12:30 PM – 1:30 PM ET 


Beatriz Noriega-Fernandes Inhalation and Advanced Drug Delivery R&D | Hovione



Presenting Author: Beatriz Noriega-Fernandes - Scientist, Inhalation and Advanced Drug Delivery Group, R&D


Although drug delivery to the lung presents several advantages, its therapeutic efficiency is limited by a rapid clearance. Thus, this poster presentation will focus on the development of sustained release formulations suitable for lung delivery.  The main goal will be to assess the impact of encapsulating a model drug (fluticasone propionate, FP) in 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) vesicles prior to spray-drying (SD) on the final product aerodynamic performance and dissolution.




More details on PharmSci360