Evaluation of the Relaxation State of Amorphous Itraconazole Using Solution Calorimetry
Hovione poster at AAPS 2021 PharmSci 360
Track: Manufacturing and Analytical Characterization – Chemical
Monday, October 18, 2021 | 8:00 AM – 9:00 AM ET
Presenting Author: Luís Sousa - Senior Analytical Scientist, R&D Analytical Development
Investigation of the relaxation phenomena in amorphous materials is key to understand and predict their physical stability. The work presented demonstrates the potential of solution calorimetry for monitoring changes in the relaxation state of amorphous materials. The advantage of this technique over traditional methods (XRPD) used for quantifying the amorphous/crystalline content is also demonstrated.